BDBM50304501 6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine::CHEMBL473662

SMILES CN1CCN(CC1)c1cc(N)nc(N)n1

InChI Key InChIKey=RBHNSRTVBDSNLG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304501   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50304501(6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine |...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50304501(6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine |...)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50304501(6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine |...)
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed