BDBM50304782 CHEMBL609583::N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamide
SMILES ONC(=O)c1cnc(nc1)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1
InChI Key InChIKey=MUTBJZVSRNUIHA-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50304782
TargetHistone deacetylase 5(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Ortho-Biotech Oncology Research & Development
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair