BDBM50306211 CHEMBL611317::{[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dipropoxypentacyclo[19.3.1.1^{3,7}.1^{9,13}.1^{15,19}]octacosa-1(25),3,5,7(28),9,11,13(27),15(26),16,18,21,23-dodecaen-5-yl](phosphono)methyl}phosphonic acid

SMILES CCCOc1c2Cc3cc(cc(Cc4cccc(Cc5cc(cc(Cc1ccc2)c5O)C(P(O)(O)=O)P(O)(O)=O)c4OCCC)c3O)C(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=ZIWTXPWHTXLQTF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50306211   

TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human recombinant PTPbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed