BDBM50306492 2-(5-((2R,5S)-4-(bis(4-fluorophenyl)methyl)-2,5-dimethylpiperazine-1-carbonyl)-6-chloro-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide::CHEMBL600470

SMILES C[C@H]1CN([C@H](C)CN1C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

InChI Key InChIKey=CQJVPZUAZOIVGF-VQTJNVASSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306492   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50306492(2-(5-((2R,5S)-4-(bis(4-fluorophenyl)methyl)-2,5-di...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed