BDBM50307443 3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino}-carbonyl)-4-[(3-methoxyphenoxy)methyl]phenyl}propanoic acid::CHEMBL599405

SMILES COc1cccc(OCc2ccc(CCC(O)=O)c(c2)C(=O)NC(CC(C)C)c2cc(C)cc(C)c2)c1

InChI Key InChIKey=KEVNXEQSUVGTNP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307443   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307443(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307443(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed