BDBM50307772 5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxypentanamide::CHEMBL599398

SMILES COc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCCCC(=O)NO

InChI Key InChIKey=YTSHEQYHNLLMSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307772   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307772(5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Curis

Curated by ChEMBL
LigandPNGBDBM50307772(5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed