BDBM50307932 CHEMBL597402::N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(perfluorophenoxy)-acetamide
SMILES Fc1c(F)c(F)c(OCC(=O)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)c(F)c1F
InChI Key InChIKey=MIODRZONQPVCRF-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50307932
Affinity DataIC50: 23.6nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by western blotMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured at 1 hr by Western blot...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured after 8 hrs by Western ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of wild type human EGFR tyrosine kinase assessed as Ulight-CAGAGAIETDKEYYTVKD phosphorylation after 15 mins by time-resolved fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by western blotMore data for this Ligand-Target Pair