BDBM50308306 (S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-(naphthalen-1-ylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate::CHEMBL597998

SMILES CC(C)(C)OC(=O)N1Cc2cc(OCC(=O)NO)ccc2C[C@H]1C(=O)Nc1cccc2ccccc12

InChI Key InChIKey=FJHLPNIMFHUWIS-QHCPKHFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308306   

TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308306((S)-tert-Butyl 7-(2-(hydroxyamino)-2-oxoethoxy)-3-...)
Affinity DataIC50:  4.25E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed