BDBM50309672 (2S,6S,2R)-2-[6-(2-Isopropylsulfonyloxy-2-phenylethyl)-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride::CHEMBL599268

SMILES CC(C)S(=O)(=O)O[C@@H](C[C@@H]1CCC[C@H](CC(=O)c2ccccc2)N1C)c1ccccc1

InChI Key InChIKey=UQYNEETUBPDCRA-CUYJMHBOSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309672   

TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309672((2S,6S,2R)-2-[6-(2-Isopropylsulfonyloxy-2-phenylet...)
Affinity DataKi:  2.09E+3nMAssay Description:Displacement of [3HDTBZ from VMAT2 in rat whole brain vesicles by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309672((2S,6S,2R)-2-[6-(2-Isopropylsulfonyloxy-2-phenylet...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309672((2S,6S,2R)-2-[6-(2-Isopropylsulfonyloxy-2-phenylet...)
Affinity DataKi:  1.61E+4nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed