BDBM50309808 CHEMBL597094::Cis-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporphine

SMILES C[C@@H]1Cc2ccc3C[C@H]4N(C)CCc5cccc(c45)-c3c2O1

InChI Key InChIKey=MSFBLSXHRFJARJ-SJKOYZFVSA-N

Data  6 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50309808   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at 5HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50309808(CHEMBL597094 | Cis-N-Methyl-2'-methyl-2',3'-dihydr...)
Affinity DataIC50:  323nMAssay Description:Agonist activity at 5HT1A receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed