BDBM50310146 BI-90H10::CHEMBL599111::N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine

SMILES COc1ccc(CCNc2nnc(Sc3ncc(s3)[N+]([O-])=O)s2)cc1OC

InChI Key InChIKey=IFYDDUABVTWOCJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310146   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50:  100nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFurin(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(BI-90H10 | CHEMBL599111 | N-(3,4-Dimethoxyphenethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed