BDBM50310147 BI-98A10::CHEMBL599518::N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine

SMILES CCC(C)Nc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1

InChI Key InChIKey=WUIDPYLIBFVBIQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310147   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50:  140nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFurin(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | CHEMBL599518 | N-sec-Butyl-5-(5-nitroth...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed