BDBM50310148 BI-90H9::CHEMBL611079::N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine

SMILES COCCNc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1

InChI Key InChIKey=BEWZDJYSVBMQJT-UHFFFAOYSA-N

Data  7 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50310148   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50:  160nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50:  280nMAssay Description:Inhibition of JNK1 (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataKd:  2.80E+3nMAssay Description:Inhibition of wild-type JNK2 by isothermal calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFurin(Homo sapiens (Human))
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | CHEMBL611079 | N-(2-Methoxyethyl)-5-(5-n...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed