BDBM50312678 CHEMBL1076674::N-{(Succinylpodophyllotoxinyl)pent-5-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl}acetamide

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCCCCCNC(=O)CCC(=O)O[C@H]3[C@@H]4COC(=O)[C@H]4[C@@H](c4cc(OC)c(OC)c(OC)c4)c4cc5OCOc5cc34)c2c1

InChI Key InChIKey=QFVXUGFOHBLZGX-FNAMUTLDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312678   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50312678(CHEMBL1076674 | N-{(Succinylpodophyllotoxinyl)pent...)
Affinity DataIC50:  147nMAssay Description:Inhibition of mouse COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50312678(CHEMBL1076674 | N-{(Succinylpodophyllotoxinyl)pent...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed