BDBM50312704 (S)-ethyl 2-cyclopentyl-5-hydroxy-7,7-dimethyl-3-(4-(trifluoromethyl)benzoyl)-5,6,7,8-tetrahydroquinoline-4-carboxylate::CHEMBL1080731

SMILES CCOC(=O)c1c2[C@@H](O)CC(C)(C)Cc2nc(C2CCCC2)c1C(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NUUAAEWPIAAMPD-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312704   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312704((S)-ethyl 2-cyclopentyl-5-hydroxy-7,7-dimethyl-3-(...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed