BDBM50313248 CHEMBL1086754::N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide::N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrchloride

SMILES Cc1c(cc(-c2ccccc2)n1C)C(=O)NCCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=YIHQDWZWZRGAIH-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50313248   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H] astemizole from human recombinant ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  46.2nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  61.7nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  54nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  713nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  333nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  915nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  984nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  46nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313248(CHEMBL1086754 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed