BDBM50313259 CHEMBL1081644::N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide

SMILES Cc1c(cc(-c2ccccc2)n1C)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=NUHJBHFWIFYLHK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313259   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  57nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  133nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  57nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  133nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313259(CHEMBL1081644 | N-(3-(4-(2,3-Dimethylphenyl)pipera...)
Affinity DataIC50:  11.8nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed