BDBM50313267 CHEMBL1086626::N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide

SMILES Cc1[nH]c(cc1C(=O)NCCCN1CCN(CC1)c1cccc(Cl)c1Cl)-c1ccccc1

InChI Key InChIKey=OHODDACZFUFQDV-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50313267   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  599nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  137nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  117nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  456nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H] astemizole from human recombinant ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  334nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  599nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  137nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313267(CHEMBL1086626 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed