BDBM50313296 (1R,5S)-3-(4-tert-butylphenylsulfonyl)-8-methyl-3,8-diazabicyclo[3.2.1]octane::CHEMBL1081299

SMILES CN1[C@H]2CC[C@@H]1CN(C2)S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=ODCGJTLYLSASPT-GASCZTMLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313296   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313296((1R,5S)-3-(4-tert-butylphenylsulfonyl)-8-methyl-3,...)
Affinity DataIC50:  117nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313296((1R,5S)-3-(4-tert-butylphenylsulfonyl)-8-methyl-3,...)
Affinity DataIC50:  478nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed