BDBM50314606 (5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-methyl-5-pyridin-4-yl-3,5-dihydro-4H-imidazol-4-one::(S)-2-amino-4-(2',5'-difluorobiphenyl-3-yl)-1-methyl-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one::CHEMBL1092788

SMILES CN1C(N)=N[C@](C1=O)(c1ccncc1)c1cccc(c1)-c1cc(F)ccc1F

InChI Key InChIKey=RKYFABJLGJZOBA-OAQYLSRUSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314606   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314606((5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-met...)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314606((5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-met...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314606((5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-met...)
Affinity DataIC50:  100nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed