BDBM50314754 CHEMBL1088784::N-(5-benzyl-4-phenyl-1,3-thiazol-2-yl)-4-(4,5-diethoxy-2-methylphenyl)-4-oxobutanamide

SMILES CCOc1cc(C)c(cc1OCC)C(=O)CCC(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1

InChI Key InChIKey=JNJQFLCWWUSMFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314754   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314754(CHEMBL1088784 | N-(5-benzyl-4-phenyl-1,3-thiazol-2...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed