BDBM50314906 1'-(7-methyl-1H-indazole-5-carbonyl)-6-(1-methyl-1H-pyrazol-3-yl)spiro[chroman-2,4'-piperidin]-4-one::CHEMBL1088893

SMILES Cc1cc(cc2cn[nH]c12)C(=O)N1CCC2(CC1)CC(=O)c1cc(ccc1O2)-c1ccn(C)n1

InChI Key InChIKey=OUTOUIHMLWJXDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314906   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314906(1'-(7-methyl-1H-indazole-5-carbonyl)-6-(1-methyl-1...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314906(1'-(7-methyl-1H-indazole-5-carbonyl)-6-(1-methyl-1...)
Affinity DataIC50:  31nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed