BDBM50315041 (R)-N-(2-(1-(2-(4-(4-methylbenzoyl)piperazin-1-yl)ethyl)pyrrolidin-3-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide::CHEMBL1093153

SMILES Cc1ccc(cc1)C(=O)N1CCN(CCN2CC[C@H](C2)NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)CC1

InChI Key InChIKey=ZKGKTICIIGFEPN-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315041   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315041((R)-N-(2-(1-(2-(4-(4-methylbenzoyl)piperazin-1-yl)...)
Affinity DataIC50:  3.46E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315041((R)-N-(2-(1-(2-(4-(4-methylbenzoyl)piperazin-1-yl)...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed