BDBM50315044 CHEMBL1090148::N-(2-((3R)-1-(1-(4-benzoylpiperazin-1-yl)propan-2-yl)pyrrolidin-3-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide

SMILES CC(CN1CCN(CC1)C(=O)c1ccccc1)N1CC[C@H](C1)NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=FPRIQQJLAIFZQG-PIFIWZBESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315044   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315044(CHEMBL1090148 | N-(2-((3R)-1-(1-(4-benzoylpiperazi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315044(CHEMBL1090148 | N-(2-((3R)-1-(1-(4-benzoylpiperazi...)
Affinity DataIC50:  1.86E+3nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed