BDBM50316641 1-(2-ethoxyethyl)-3-methyl-N7-(4-methylpyridin-2-yl)-N5-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-d]pyrimidine-5,7-diamine::CHEMBL1094490

SMILES CCOCCn1nc(C)c2nc(NC3CCOCC3)nc(Nc3cc(C)ccn3)c12

InChI Key InChIKey=GCJUZOXOALBRLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316641   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316641(1-(2-ethoxyethyl)-3-methyl-N7-(4-methylpyridin-2-y...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed