BDBM50318111 (S)-3-(4-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-oxo-1,2-dihydropyridin-3-yl)-4-methyl-1H-benzo[d]imidazol-6-yl)piperazin-1-yl)propanenitrile::CHEMBL1094164

SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NC[C@@H](O)c2cccc(Cl)c2)cc[nH]c1=O)N1CCN(CCC#N)CC1

InChI Key InChIKey=VVIPLSCLYCWUQT-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318111   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50318111((S)-3-(4-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50:  61nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50318111((S)-3-(4-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4 assessed as dealkylation of 7-benzyloxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed