BDBM50319797 (4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone::CHEMBL1083703

SMILES COc1cc(ccc1-c1csc2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2

InChI Key InChIKey=UXYNEKLEPXVKQZ-WXTAPIANSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319797   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
Affinity DataKi:  0.790nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
Affinity DataKi:  15nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human Vasopressin V1a receptor assessed as inhibition of intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
Affinity DataIC50:  838nMAssay Description:Antagonist activity at human Vasopressin 2 receptor assessed as inhibition of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed