BDBM50320272 (S)-1-(1-cyclopropylethyl)-5-(2,6-dichloro-4-methoxyphenylamino)-3-methyl-1,2,4-triazin-6(1H)-one::CHEMBL1082309

SMILES COc1cc(Cl)c(Nc2nc(C)nn([C@@H](C)C3CC3)c2=O)c(Cl)c1

InChI Key InChIKey=FHRBLGNXGIAMBR-QMMMGPOBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320272   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50320272((S)-1-(1-cyclopropylethyl)-5-(2,6-dichloro-4-metho...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]Tyr-ovine CRF from rat CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed