BDBM50322418 CHEMBL1173195::Octanethioic acid S-[(E)-4-((8S,11S)-8-isopropyl-6,9,13-trioxo-10-oxa-3,17-dithia-7,14,19,20-tetraaza-tricyclo[14.2.1.1*2,5*]icosa-1(18),2(20),4,16(19)-tetraen-11-yl)-but-3-enyl]ester
SMILES CCCCCCCC(=O)SCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)-c2nc(cs2)C(=O)N[C@@H](C(C)C)C(=O)O1
InChI Key InChIKey=XWGHGIMKSBEUMD-SLQHSKKLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50322418
TargetHistone deacetylase 3(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant HDAC1 after 15 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 after 15 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair