BDBM50323672 (1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]-3-azabicyclo[3.2.1]octane hydrochloride::CHEMBL1209124::rac-exo-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]-3-azabicyclo[3.2.1]octane

SMILES Oc1cncc(c1)-c1ccccc1O[C@H]1C[C@H]2C[C@@H]1CNC2

InChI Key InChIKey=WXTQMACZCSXJTB-DFHBCGBQSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50323672   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  252nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  255nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323672((1R,6S,5R)-[6-(2-(5-Hydroxypyridin-3-yl)phenoxy))]...)
Affinity DataKi: >1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha7 nicotinic receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed