BDBM50326676 4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)benzenesulfonamide::CHEMBL1254856

SMILES Nc1nc(N)c2nc(CNCCc3ccc(cc3)S(N)(=O)=O)cnc2n1

InChI Key InChIKey=WCRHQBWCHFXCQJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326676   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  45nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  2.74E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed