BDBM50328099 2,2-Dimethyl-N-(2-morpholin-4-ylethyl)-5-pyrrolidin-1-yl-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine::CHEMBL1258470

SMILES CC1(C)CCc2c(C1)c1c(nc2N2CCCC2)sc2c(NCCN3CCOCC3)ncnc12

InChI Key InChIKey=XNIYDLUVCSJKFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328099   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328099(2,2-Dimethyl-N-(2-morpholin-4-ylethyl)-5-pyrrolidi...)
Affinity DataIC50:  8.05nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328099(2,2-Dimethyl-N-(2-morpholin-4-ylethyl)-5-pyrrolidi...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328099(2,2-Dimethyl-N-(2-morpholin-4-ylethyl)-5-pyrrolidi...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed