BDBM50328725 (R)-N1-(4-chlorophenyl)-N2-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)pyrrolidine-1,2-dicarboxamide::4-Substituted Pyrrolidine Ring, 1::CHEMBL1271371::P1 Phenyl Ring, 23

SMILES NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)[C@H]2CCCN2C(=O)Nc2ccc(Cl)cc2)c(F)c1

InChI Key InChIKey=BTWQGZKVIXMIOP-OAQYLSRUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328725   

TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

LigandPNGBDBM50328725((R)-N1-(4-chlorophenyl)-N2-(3-fluoro-2'-sulfamoylb...)
Affinity DataIC50:  36nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

LigandPNGBDBM50328725((R)-N1-(4-chlorophenyl)-N2-(3-fluoro-2'-sulfamoylb...)
Affinity DataIC50:  18nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

LigandPNGBDBM50328725((R)-N1-(4-chlorophenyl)-N2-(3-fluoro-2'-sulfamoylb...)
Affinity DataIC50:  18nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed