BDBM50329892 2-chloro-N-(6-(4-(chloromethyl)-6-hydroxypyrimidin-2-yl)pyridin-3-yl)acetamide::CHEMBL1269467

SMILES ClCC(=O)Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1

InChI Key InChIKey=GMVTYGJRSLQMKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329892   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329892(2-chloro-N-(6-(4-(chloromethyl)-6-hydroxypyrimidin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329892(2-chloro-N-(6-(4-(chloromethyl)-6-hydroxypyrimidin...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed