BDBM50332368 (S)-2-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl)isoindoline-4-carbonitrile::CHEMBL1631016
SMILES C[C@H](Oc1ccc(cc1C(=O)N1Cc2cccc(C#N)c2C1)S(C)(=O)=O)C(F)(F)F
InChI Key InChIKey=KZTUEUOKPCKYBS-LBPRGKRZSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50332368
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 770nMAssay Description:Inhibition of human GlyT1 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human GlyT2 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation countingMore data for this Ligand-Target Pair