BDBM50333057 4-{3-[4-(3-Adamantan-1-yl-ureido)-phenoxy]-propyl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL1632490

SMILES CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(NC(=O)NC34CC5CC(CC(C5)C3)C4)cc2)CC1

InChI Key InChIKey=QBHOJOZHMOMXHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333057   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50333057(4-{3-[4-(3-Adamantan-1-yl-ureido)-phenoxy]-propyl}...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50333057(4-{3-[4-(3-Adamantan-1-yl-ureido)-phenoxy]-propyl}...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus expression system by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed