BDBM50335505 1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid::CHEMBL1651851

SMILES OC(=O)C1CN(Cc2ccc(-c3nc4nc(Cc5ccccc5)ccc4s3)c(F)c2)C1

InChI Key InChIKey=WCLORTHIBMHSSY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335505   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335505(1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  144nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335505(1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  1.01E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed