BDBM50335508 1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid::CHEMBL1651854

SMILES OC(=O)C1CN(Cc2ccc(-c3nc4ccc(Cc5ccccc5)cc4s3)c(F)c2)C1

InChI Key InChIKey=YHUJYSUWHIWQKN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335508   

TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  221nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  221nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed