BDBM50335509 1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid::CHEMBL1651853

SMILES OC(=O)C1CN(Cc2ccc(-c3nc4cc(Cc5ccccc5)cnc4s3)c(F)c2)C1

InChI Key InChIKey=QMNUVBHTCZWIBM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335509   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335509(1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  138nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335509(1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  2.89E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed