BDBM50336149 (1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycyclopentyl)isoxazole-3-carboxamide::CHEMBL1669537

SMILES O[C@H]1CC[C@H](C1)NC(=O)c1noc(c1Cl)-c1ccc(F)cc1

InChI Key InChIKey=NPYDABASBGPJSZ-MNOVXSKESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336149   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Sharpe And Dohme

Curated by ChEMBL
LigandPNGBDBM50336149((1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycy...)
Affinity DataIC50:  434nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed