BDBM50336463 (3S,5R,Z)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione::CHEMBL1668417
SMILES COc1cc(O)c2c(c1)\C=C/CCCC(=O)C[C@H](Br)C[C@H](C)OC2=O
InChI Key InChIKey=OWTUABVVXBPDCL-MDUKQBBOSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50336463
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University Of Ireland
Curated by ChEMBL
National University Of Ireland
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair