BDBM50336917 3-chloro-N-(4-chlorophenyl)-5-(4,5-dimethyl-1-propyl-1H-imidazol-2-yl)pyridin-2-amine::CHEMBL1672440

SMILES CCCn1c(C)c(C)nc1-c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=MHNVIGLBIPNJGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336917   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336917(3-chloro-N-(4-chlorophenyl)-5-(4,5-dimethyl-1-prop...)
Affinity DataIC50:  250nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed