BDBM50337318 5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682349

SMILES Clc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1

InChI Key InChIKey=QLPKEICBTKFRKM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337318   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337318(5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  68nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337318(5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  186nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337318(5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  197nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337318(5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337318(5-(1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  3.78E+4nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed