BDBM50337916 (+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,3-dimethylbutan-1-amine::CHEMBL1684046::US10562878, Compound 45
SMILES CNC(CC(C)C)C1(CCCCC1)c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=POKCWLLPLOIIOW-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50337916
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 964nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]dopamine reuptake at human human recombinant DAT expressed in COS-7 cells by scintillation countingMore data for this Ligand-Target Pair