BDBM50338224 1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-(2,4-difluorobenzyl)urea::CHEMBL1681954

SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCc2ccc(F)cc2F)c(Cl)c1

InChI Key InChIKey=RNCPKNKPKGTQPT-HIUVJMHLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338224   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338224(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed