BDBM50338264 CHEMBL1682018::N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-5-yl)acetamide
SMILES O=C(Cc1cccc2cnccc12)Nc1scc(C#N)c1-c1nnc[nH]1
InChI Key InChIKey=VINQLWACVZJJIO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50338264
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant ERK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair