BDBM50339046 5-(2-((1H-imidazol-5-yl)methylamino)pyridin-3-yl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazol-2-amine::CHEMBL1688350

SMILES C(Nc1ncccc1-c1nnc(Nc2ccc3OCCOc3c2)o1)c1cnc[nH]1

InChI Key InChIKey=GGPXVYPZTUORQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339046   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339046(5-(2-((1H-imidazol-5-yl)methylamino)pyridin-3-yl)-...)
Affinity DataIC50:  830nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339046(5-(2-((1H-imidazol-5-yl)methylamino)pyridin-3-yl)-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addtion of substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed