BDBM50340800 3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,2,4-triazol-3-yl)-3-methoxyphenyl)pyridine::CHEMBL1760803
SMILES COc1cc(ccc1-c1nnc(n1C)C1(CCC1)c1ccc(Cl)cc1)-c1cccnc1
InChI Key InChIKey=RBGKTPBXYABVOH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50340800
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataEC50: 4.60E+3nMAssay Description:Agonist activity at PXRMore data for this Ligand-Target Pair