BDBM50341294 CHEMBL1766032::N'-(3-Hydroxybenzyl)-aminothiazolo[5,4-b]-N-cyclopropylmethyl-morphinan

SMILES Oc1cccc(CNc2nc3cc4c(C[C@@H]5[C@@H]6CCCC[C@]46CCN5CC4CC4)cc3s2)c1

InChI Key InChIKey=LBJQLPJWKUBKAZ-UTOLSJPLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341294   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50341294(CHEMBL1766032 | N'-(3-Hydroxybenzyl)-aminothiazolo...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50341294(CHEMBL1766032 | N'-(3-Hydroxybenzyl)-aminothiazolo...)
Affinity DataKi:  9.90nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50341294(CHEMBL1766032 | N'-(3-Hydroxybenzyl)-aminothiazolo...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]Naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed