BDBM50341817 (1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766901

SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2nc3cc(Cl)ccn3c2s1)C(O)=O

InChI Key InChIKey=KFOJCCXBEQXGOL-JSZUHDFRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341817   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341817((1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341817((1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341817((1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341817((1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed